Assessment of iron deficiency status in patients with juvenile idiopathic arthritis
using indexed indicators
Strogaya N.V., Zaitseva E.S., Tarasova E.S.
Belarussian State Medical University, Minsk, Belarus
The article presents the results of a study of indexed indicators of erythropoiesis in patients with juvenile idiopathic arthritis (JIA).
The aim of the study was to examine iron metabolism in patients with JIA using modern calculated erythrocyte parameters.
Material and methods: the study of the state of iron metabolism using calculated indicators was carried out among 100 patients with JIA and 30 practically healthy children.
Results. Based on the results obtained, in the study group and the comparison group, both studied indicators had statistically significant differences. The presence of the disease influenced the value of both MAF (H=7.4) and LHD% (H=8.58). According to the results of the ROC analysis, MAF has more pronounced advantages compared to LHD for detecting disorders in iron metabolism at the level of assessing erythrocyte parameters in patients with JIA, which can be useful in diagnostics.
Conclusion. The calculated MAF and LHD indicators characterize the change in size of erythrocytes and the decrease in hemoglobin content in the cell. The calculation of MAF and LHD values allows to detect iron deficiency regardless of the presence of disease activity.