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International journal of Immunopathology, allergology, infectology.

Clinical and immunological characteristics of pediatric patients with stomatitis

Kuzmenkova A.V.

Vitebsk State Medical University, Vitebsk, Belarus

The aim of study. To study the local immune status in pediatric patients diagnosed with stomatitis.
Objects and methods. The work is based on a retrospective and prospective analyses result research among 120 pediatric patients (4-12 years old) with stomatitis.
Results. The results of patients' immunological examination with stomatitis are described. Research data (clinical, immunological) were analyzed using STATISTICA 10.0 software.
In patients of the primary physical and histological period, the concentrations of α-amylase, lysozyme, myeloperoxidase, and secretory immunoglobulin A are increased. There is a lack of local immunity and production of immunoglobulin M.
In pediatric patients related to the secondary period of physical and histological age features, the production of lysozyme, lactoferrin and myeloperoxidase, as well as immunoglobulin M and secretory immunoglobulin A, is reduced.
Conclusion. From the results of this research, it is evident that there is a correlation between the physico-histological and immunological characteristics in children diagnosed with stomatitis.

Keywords

Children, stomatitis, lysozyme, lactoferrin, myeloperoxidase, secretory immunoglobulin A, immunoglobulin M

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DOI

10.14427/jipai.2022.3.77

Reference

Kuzmenkova A.V. Immunopathology, allergology, infectology 2022; 3:77-82. DOI: 10.14427/jipai.2022.3.77