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International journal of Immunopathology, allergology, infectology.

Non-angioedema-related macroglossia: case report

Sobolenko T.M., Ishchenko O.V., Zakharov O.V., Laporevich V.B.

Vitebsk State Order of Peoples' Friendship Medical University, Vitebsk, Belarus
Vitebsk Regional Clinical Hospital, Vitebsk, Belarus

Acute macroglossia not associated with angioedema is a rare condition. We present a case of acute unilateral macroglossia of unclear etiology in a 46-year-old man. Tongue enlargement was accompanied by difficulty in talking, but did not result in upper airway obstruction. Angioedema of the tongue was excluded. The symptoms disappeared within one month. Cervical radiculopathy and COVID-19 infection are considered as probable causes of macroglossia.


Macroglossia, angioedema, tongue, cervical radiculopathy, COVID-19

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Sobolenko T.M., Ishchenko O.V., Zakharov O.V., Laporevich V.B. Immunopathology, allergology, infectology 2022; 2:51-54. DOI: 10.14427/jipai.2022.2.51