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International journal of Immunopathology, allergology, infectology.

The role of the antimicrobial peptide LL-37 in the development of autoimmunity in psoriasis

Pinegin B.V., Pinegin V.B.

Department of immunodiagnostics and immunocorrection, National Research Center “Institute of Immunology” of the Federal Medical-Biological Agency of Russia
Department of dermatology and venereology, 1st Moscow State Medical University

We present an analysis of literature concerning the role of the antimicrobial peptide LL-37 in the initiation and inhibition of psoriatic inflammation. Potential ways of therapeutic application of LL-37 are considered.


Psoriasis, immune system cells, cytokines, LL-37 peptide

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Pinegin B.V., Pinegin V.B. Immunopathology, allergology, infectology 2013; 1:6-12. DOI: 10.14427/jipai.2013.1.6