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International journal of Immunopathology, allergology, infectology.

Natural antibodies and their physiolodical fanctions

Myagkova M.A., Morozova V.S.

Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka, Moscow region., Russia

The review presents the results of analysis of humoral immunity factors natural antibodies which are produced in normal cells in the absence of antigenic stimulation. The questions of the survey methodology physiological fuknktsii natural antibodies. It is shown that they are complementary and regulatory molecules involved in the formation of a normal immune response, homeostatic regulation, the establishment of idiotypic repertoire and protecting the body from infection and viral agents.


Natural antibodies, homeostasis, isotype composition, immunoregulatory activity, the affinity constant, the specificity of interaction with the antigenic target.

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Myagkova M.A., Morozova V.S. Immunopathology, allergology, infectology 2014; 3:75-81